What is CBC / Cannabichromene?

    You’re likely to be familiar with CBD by now – but did you know that this is just one of over 147 cannabinoids derived from the cannabis plant? Although CBD is the most abundant cannabinoid in hemp, which is the most common form of cannabis used to create CBD products in the UK/EU, cannabinoid researchers around the world have been making ground-breaking discoveries about lesser known, minor cannabinoids.

    In today’s article, we’ll be looking at CBC – a cannabinoid with the same origins as CBD and THC, which is proving to have a raft of medicinal benefits for conditions ranging from acne to cancer.

    What is CBC?

    Cannabichromene (CBC) is, like CBD, non-psychotropic and will not get you high. It is the third most prevalent cannabinoid in cannabis and was first discovered in 1966. Since then, while it has not been at the centre of research like CBD and THC, a multitude of studies have demonstrated its impressive potential as a therapeutic agent.

    On its own, CBC has been shown to have significant anti-inflammatory, analgesic, anti-cancer and anti-depressant properties, as well as the ability to have a positive effect on the viability of neural stem progenitor cells, which are an essential component of brain function in health and pathology.

    When used in conjunction with other cannabinoids, terpenes and flavonoids, CBC is also a major player in creating the ‘entourage effect‘ – the enhancement of the therapeutic properties of cannabis when all parts work in synergy with each other.

    CBC for Depression

    Despite the fact that CBD has risen to fame largely for its anti-anxiety and anti-depressant properties, this molecule on its own actually pales in comparison to other cannabinoids, like CBC. There are multiple studies demonstrating how Cannabichromene can significantly reduce depression.

    Like every component of the cannabis plant, CBC works through a variety of mechanisms to achieve its therapeutic effects. The mood-elevating benefits are most likely to come from this cannabinoid’s ability to bind to and activate the CB2 receptor – one type of endocannabinoid receptor which, when activated, does not produce a euphoric high, like CB1, but supports the synthesis and release of the endocannabinoid anandamide, also known as the ‘bliss molecule’. Anandamide is widely acknowledged for its ability to lift mood as well as reduce stress and pain.

    CBC for Acne

    Breakthrough research has revealed how CBC may also be a valuable tool in tackling acne – one of the most common skin conditions, characterised by elevated sebum production and inflammation of the sebaceous glands. 

    In one study, CBC was found to suppress sebum production and ‘significantly reduce arachidonic acid (AA)-induced ‘acne-like’ lipogenesis’. This, alongside the potent anti-inflammatory effects of CBC, makes for exciting potential; especially when used alongside CBD which has also been shown to be beneficial in the treatment of acne. 

    CBC for Pain

    CBC seems to work best on pain when used in combination with THC – the cannabinoid most commonly used to treat pain conditions. Studies have shown that, when used together, CBC enhances the effects of THC, including its anti-inflammatory actions.

    CBC for Cancer

    Cannabis has been at the forefront of the cancer conversation for many years – not always in the most positive sense, as plenty of people will still argue its ability to shrink tumours. However, the science – which is still pouring out – most definitely indicates that cannabis could (and should) play an integral role in cancer treatment and symptom management. Pharmaceutical companies are already aware of this, as currently there are a lot of cannabinoid patents held for this exact purpose.

    CBC has produced some exciting results, with one facility in Israel undertaking tests which have shown that CBC very clearly exhibits anti-tumor properties after being tested on human gastrointestinal cancer cells.

    Further research has demonstrated that CBD can inhibit colon and breast cancer cell growth, albeit only at high doses.

    As it is a minor cannabinoid, which is harder to come by in large quantities than CBD or THC, the research into CBC’s potential is still in its early stages. However, what we have seen so far certainly offers a lot of hope for future use in medicine and commercially available products.

    You can find CBC in the following Ardoa Organics products:

    Find out more about cannabinoids: Read everything you need to know about CBDV, CBDA and CBG.

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